Question:

The linkage formed between 5' and 3' carbon atoms of the pentose sugar in nucleotides is

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Biology Tip: Sugar-phosphate backbone of DNA is formed by repeating 3'-5' phosphodiester bonds.
Updated On: Apr 24, 2026
  • glycosidic
  • phosphomonoester
  • amide
  • peptide
  • phosphodiester
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The Correct Option is

Solution and Explanation

Concept:
Nucleotides join together in DNA and RNA chains through phosphate linkages.
Step 1: Understand bonding positions.
The phosphate group connects: - $3'$ carbon of one sugar - $5'$ carbon of next sugar
Step 2: Name of linkage.
Since one phosphate forms two ester bonds with two sugars, it is called: \[ \text{Phosphodiester linkage} \]
Step 3: Final answer.
\[ \boxed{\text{Phosphodiester}} \]
Hence, correct option is (E).
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