Concept:
Reflection of a point $(x_1,y_1)$ in the line $ax + by + c = 0$ is given by:
\[
x' = x_1 - \frac{2a(ax_1 + by_1 + c)}{a^2 + b^2}
\]
\[
y' = y_1 - \frac{2b(ax_1 + by_1 + c)}{a^2 + b^2}
\]
Step 1: Identify values.
\[
a = 2, b = -3, c = 1
\]
\[
(x_1, y_1) = (2,1)
\]
Step 2: Compute $ax_1 + by_1 + c$.
\[
= 2(2) + (-3)(1) + 1
\]
\[
= 4 - 3 + 1 = 2
\]
Step 3: Compute denominator.
\[
a^2 + b^2 = 4 + 9 = 13
\]
Step 4: Find $x'$ coordinate.
\[
x' = 2 - \frac{2 \cdot 2 \cdot 2}{13}
\]
\[
= 2 - \frac{8}{13}
\]
\[
= \frac{26 - 8}{13} = \frac{18}{13}
\]
Step 5: Find $y'$ coordinate.
\[
y' = 1 - \frac{2(-3)(2)}{13}
\]
\[
= 1 + \frac{12}{13}
\]
\[
= \frac{25}{13}
\]
Final Answer:
\[
\boxed{\left(\frac{18}{13}, \frac{25}{13}\right)}
\]