Question

The gene HBB for β-thalassemia is present on which chromosome?

• A. 5
• B. 22
• C. 11
• D. 9

Answer 1

The Correct Option is C

The gene HBB, which is responsible for the condition known as β-thalassemia, is associated with coding for the beta chains of hemoglobin. It is crucial for the synthesis of normal hemoglobin A, which is the predominant form of hemoglobin in adults. Mutations in this gene affect the production of these beta chains, leading to the disorder β-thalassemia. The HBB gene is located on chromosome 11. During genetic studies and diagnostics, understanding the chromosomal location of genes is vital for identifying genetic mutations and providing accurate genetic counseling. Thus, the correct answer is chromosome 11.

Answer 2

The HBB gene, which codes for the beta-globin part of hemoglobin, is located on chromosome 11. Mutations in the HBB gene can lead to β-thalassemia, a blood disorder that affects hemoglobin production.

Thus, the correct answer is (3) 11.