Question

Match List-I with List-II:

List-I	List-II
(A) Thalassemia	(I) 47, XXY
(B) Klinefelter’s syndrome	(II) Sex-linked recessive disorder
(C) Turner’s syndrome	(III) 45, XO
(D) Colour blindness	(IV) Autosomal recessive disease

• A. (A)-(IV), (B)-(II), (C)-(I), (D)-(III)
• B. (A)-(II), (B)-(I), (C)-(III), (D)-(IV)
• C. (A)-(II), (B)-(IV), (C)-(III), (D)-(I)
• D. (A)-(IV), (B)-(I), (C)-(III), (D)-(II)

Answer 1

The Correct Option is D

To correctly match List-I with List-II, we need to understand the characteristics of each term: 

• Thalassemia: This is an autosomal recessive disease caused by mutations affecting hemoglobin synthesis, leading to anemia.
• Klinefelter’s syndrome: This genetic condition in males is due to the presence of an extra X chromosome, resulting in a karyotype of 47, XXY.
• Turner’s syndrome: A chromosomal disorder where a female is missing part of or an entire X chromosome, leading to a 45, XO karyotype.
• Colour blindness: A sex-linked recessive disorder typically affecting the ability to perceive certain colors correctly, most commonly red-green color blindness.

Using these descriptions, the correct matches are:

List-I	List-II
(A) Thalassemia	(IV) Autosomal recessive disease
(B) Klinefelter’s syndrome	(I) 47, XXY
(C) Turner’s syndrome	(III) 45, XO
(D) Colour blindness	(II) Sex-linked recessive disorder

The correct answer is: (A)-(IV), (B)-(I), (C)-(III), (D)-(II)

Answer 2

Let’s match each condition with its correct description: 

(A) Thalassemia: Thalassemia is an autosomal recessive disease. It is an inherited blood disorder that causes abnormal hemoglobin production, and individuals with two copies of the defective gene (one from each parent) express the disease.

(B) Klinefelter’s syndrome: Klinefelter's syndrome is a sex chromosome aneuploidy where the individual has an extra X chromosome, resulting in a 47, XXY karyotype. This condition affects males, leading to features such as infertility and developmental delays.

(C) Turner’s syndrome: Turner’s syndrome occurs when a female has only one X chromosome, resulting in a 45, XO karyotype. It leads to short stature, infertility, and other physical features.

(D) Colour blindness: Colour blindness is a sex-linked recessive disorder, primarily affecting males, and is typically carried on the X chromosome.

Therefore, the correct matches are:

(A) Thalassemia → (IV) Autosomal recessive disease

(B) Klinefelter’s syndrome → (I) 47, XXY

(C) Turner’s syndrome → (III) 45, XO

(D) Colour blindness → (II) Sex-linked recessive disorder

The correct answer is (4) (A)-(IV), (B)-(I), (C)-(III), (D)-(II).