Question

The following table depicts Characteristics of various arms of tRNA (Column I) and the name of the arms of tRNA(Column II)
{ll} Characteristics of arm (Column I) & Name of the arm of tRNA(Column II)
A. It consists of base paired stem that terminates in the sequence CCA (5’ to 3’) & I. Anticodon arm
B. It recognizes the codon & II. Acceptor arm
C. Contains the base dihydrouridine & III. T $\Psi$ C arm
D. Contains the sequence pseudouridine & IV. D arm

• A. A-I, B-II, C-III, D-IV
• B. A-II, B-I, C-IV, D-III
• C. A-II, B-III, C-I, D-IV
• D. A-I, B-III, C-II, D-IV

Hint:

D arm = Dihydrouridine
T $\Psi$ C arm = Pseudouridine ($\Psi$)
Acceptor arm = Amino acid attachment site (CCA)

Answer 1

The Correct Option is B

Step 1: Understanding the Concept:
Transfer RNA (tRNA) is an adapter molecule that translates genetic information from mRNA codons into a sequence of amino acids.
tRNA folds into a highly conserved secondary structure resembling a cloverleaf, consisting of four primary arms.

Step 2: Detailed Explanation:
Let us match the characteristics of each arm in Column I to its correct name in Column II:
A: The stem that terminates in the conserved $5'$ to $3'$ sequence CCA is where the amino acid is covalently attached. This is the Acceptor arm (II).
B: The loop that contains three nucleotide bases complementary to the mRNA codon is the Anticodon arm (I).
C: The arm that contains the modified base dihydrouridine (D) is the D arm (IV).
D: The loop that contains the conserved sequence ribothymidine, pseudouridine ($\Psi$), and cytidine is the T $\Psi$ C arm (III).
Matching these pairs results in: A-II, B-I, C-IV, D-III.

Step 3: Final Answer:
The correct matches are A-II, B-I, C-IV, and D-III, which corresponds to Option (B).