Step 1: Understanding the Question:
We need to find the line equation that cuts perfectly through the midpoint of the segment joining points $A$ and $B$ at a right angle ($90^\circ$).
Step 2: Key Formula or Approach:
1. Find the coordinates of the midpoint $M$ using the midpoint formula:
$$M = \left(\frac{x_1 + x_2}{2}, \frac{y_1 + y_2}{2}\right)$$
2. Find the slope of segment $AB$: $m_{AB} = \frac{y_2 - y_1}{x_2 - x_1}$.
3. Calculate the perpendicular slope: $m_{\perp} = -\frac{1}{m_{AB}}$.
4. Substitute the point $M$ and slope $m_{\perp}$ into the point-slope formula: $y - y_1 = m(x - x_1)$.
Step 3: Detailed Explanation:
Let's first calculate the midpoint $M$ of the segment $AB$:
$$M = \left(\frac{-2 + 6}{2}, \frac{3 + (-5)}{2}\right) = \left(\frac{4}{2}, \frac{-2}{2}\right) = (2, -1)$$
Now, let's find the slope of line segment $AB$:
$$m_{AB} = \frac{-5 - 3}{6 - (-2)} = \frac{-8}{8} = -1$$
Since the bisector line is perpendicular to $AB$, its slope must be the negative reciprocal:
$$m_{\perp} = -\frac{1}{-1} = 1$$
Using the point-slope form with slope $m = 1$ passing through the midpoint $(2, -1)$:
$$y - (-1) = 1(x - 2)$$
$$y + 1 = x - 2$$
Rearranging into standard form:
$$x - y = 3$$
Step 4: Final Answer:
The equation of the perpendicular bisector is $x - y = 3$, which matches option (D).