Question

The correct sequence of transmission of pain/nociceptive stimulus from distal to proximal is:
A. Lateral spinothalamic tract
B. Transmission cells or T cells/Interneurons
C. Third order neuron
D. Dorsal root
E. Cerebral cortex
Choose the correct answer from the options given below:

• A. D, B, A, E, C
• B. D, B, A, C, E
• C. D, B, C, A, E
• D. B, D, C, A, E

Hint:

Pain pathway: Dorsal root → Spinal cord → Spinothalamic tract → Thalamus → Cortex

Answer 1

The Correct Option is B

Concept:
Pain transmission follows the spinothalamic pathway involving three-order neurons:
• First-order neuron → Peripheral to spinal cord
• Second-order neuron → Spinal cord to thalamus
• Third-order neuron → Thalamus to cortex

Step 1: Entry through dorsal root.

• Nociceptive signals enter spinal cord via dorsal root Thus: \[ D: Dorsal root \]

Step 2: Synapse in spinal cord.

• First-order neuron synapses with interneurons/T cells Thus: \[ B: Transmission cells \]

Step 3: Ascending tract.

• Second-order neurons ascend via lateral spinothalamic tract Thus: \[ A: Lateral spinothalamic tract \]

Step 4: Third-order neuron.

• Signal relayed from thalamus to cortex Thus: \[ C: Third-order neuron \]

Step 5: Perception in cortex.

• Final processing in cerebral cortex Thus: \[ E: Cerebral cortex \]

Step 6: Final sequence.
\[ D \rightarrow B \rightarrow A \rightarrow C \rightarrow E \] \[ \boxed{\text{Correct answer = Option (2)}} \]