Question:
The codons causing gene termination are:
The codons causing gene termination are:
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Remember stop codons with the mnemonic: "U Are Annoying" (UAA), "U Are Gone" (UAG), "U Go Away" (UGA).
Updated On: Jul 2, 2026
- UAA
- UAG
- UUU
- UGA
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The Correct Option is A
Approach Solution - 1
The three stop codons in molecular biology are:
UAA (Ochre)
UAG (Amber)
UGA (Opal) UUU codes for phenylalanine (Phe) and is not a termination codon.
UAA (Ochre)
UAG (Amber)
UGA (Opal) UUU codes for phenylalanine (Phe) and is not a termination codon.
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Approach Solution -2
Reasoning from the genetic code table and release factors:
A termination codon is one for which no aminoacyl-tRNA exists, instead a release factor protein binds the ribosome and ends translation.
Checking UUU first, it does correspond to a tRNA, it codes for the amino acid phenylalanine, so it cannot be a stop codon.
UAA, historically called the "ochre" codon, has no matching tRNA and is recognised directly by release factors (RF1 in bacteria, eRF1 in eukaryotes), causing the ribosome to release the completed polypeptide.
This release-factor recognition, rather than amino-acid coding, is what makes UAA a genuine termination codon.
A termination codon is one for which no aminoacyl-tRNA exists, instead a release factor protein binds the ribosome and ends translation.
Checking UUU first, it does correspond to a tRNA, it codes for the amino acid phenylalanine, so it cannot be a stop codon.
UAA, historically called the "ochre" codon, has no matching tRNA and is recognised directly by release factors (RF1 in bacteria, eRF1 in eukaryotes), causing the ribosome to release the completed polypeptide.
This release-factor recognition, rather than amino-acid coding, is what makes UAA a genuine termination codon.
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