Question:
The chelating ligand used to remove excess of copper and iron in chelate therapy is
The chelating ligand used to remove excess of copper and iron in chelate therapy is
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Higher denticity ⇒ stronger chelation ⇒ EDTA (hexadentate) is most powerful.
Updated On: May 8, 2026
- D-Penicillamine
- Oxalate ion
- EDTA
- Ethylene diamine
- Dimethyl glyoxime
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The Correct Option is C
Solution and Explanation
Concept:
Chelation therapy uses ligands that can form multiple bonds (multidentate ligands) with metal ions to remove them from the body.
Step 1: Identify strongest chelating ligand EDTA is a hexadentate ligand → binds metal ions strongly and forms very stable complexes.
Step 2: Application EDTA is widely used in:
• Lead poisoning
• Excess Cu and Fe removal
Step 3: Reject others
• D-Penicillamine: specific for Cu (Wilson disease)
• Oxalate: weak ligand
• Ethylenediamine: bidentate only
• Dimethylglyoxime: specific for Ni \[ \boxed{\text{EDTA is correct}} \]
Step 1: Identify strongest chelating ligand EDTA is a hexadentate ligand → binds metal ions strongly and forms very stable complexes.
Step 2: Application EDTA is widely used in:
• Lead poisoning
• Excess Cu and Fe removal
Step 3: Reject others
• D-Penicillamine: specific for Cu (Wilson disease)
• Oxalate: weak ligand
• Ethylenediamine: bidentate only
• Dimethylglyoxime: specific for Ni \[ \boxed{\text{EDTA is correct}} \]
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