Question:
The cells which participate in the osteogenesis are
(A) Osteoclasts
(B) Osteoblasts
(C) Osteocytes
(D) Fibrocytes
Choose the correct answer from the options given below:
The cells which participate in the osteogenesis are
(A) Osteoclasts
(B) Osteoblasts
(C) Osteocytes
(D) Fibrocytes
Choose the correct answer from the options given below:
(A) Osteoclasts
(B) Osteoblasts
(C) Osteocytes
(D) Fibrocytes
Choose the correct answer from the options given below:
Show Hint
- Osteoblasts = Bone builders.
- Osteoclasts = Bone carvers/consumers.
- Osteocytes = Bone regulators/mechanosensors.
- Osteoclasts = Bone carvers/consumers.
- Osteocytes = Bone regulators/mechanosensors.
Updated On: Jul 23, 2026
- (A), (B) and (D) only.
- (A), (B) and (C) only.
- (A), (B), (C) and (D).
- (B) and (C) only.
Show Solution
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The Correct Option is B
Solution and Explanation
Step 1: Understanding the Concept:
Osteogenesis is the biological process of bone tissue formation, remodeling, and maintenance.
This process requires coordinated interactions between three specialized resident bone cell types, whereas general fibrous connective tissue cells are not directly involved.
Step 2: Detailed Explanation:
Let us evaluate each of the cell types listed regarding their participation in bone formation and remodeling:
- (A) Osteoclasts:
These are large, multinucleated, giant cells derived from the monocyte-macrophage lineage.
They are responsible for bone resorption (dissolving bone matrix and mineral), which is a critical phase of osteogenesis and continuous bone remodeling.
Therefore, (A) is involved.
- (B) Osteoblasts:
These are mononuclear, bone-forming cells derived from osteoprogenitor cells.
They synthesize and secrete the organic components of the bone matrix (osteoid) and facilitate its subsequent mineralization.
Therefore, (B) is involved.
- (C) Osteocytes:
These are mature bone cells trapped within lacunae in the mineralized bone matrix, derived from osteoblasts.
They act as mechanosensors and orchestrate the activity of both osteoblasts and osteoclasts, maintaining bone tissue homeostasis.
Therefore, (C) is involved.
- (D) Fibrocytes:
These are resting, inactive cells of general connective tissue proper (such as in tendons or ligaments) and do not participate directly in the specialized process of osteogenesis.
Therefore, (D) is not involved.
Thus, (A) Osteoclasts, (B) Osteoblasts, and (C) Osteocytes are the cell types that participate in osteogenesis.
Step 3: Final Answer:
The correct option is (B), representing (A), (B) and (C) only.
Osteogenesis is the biological process of bone tissue formation, remodeling, and maintenance.
This process requires coordinated interactions between three specialized resident bone cell types, whereas general fibrous connective tissue cells are not directly involved.
Step 2: Detailed Explanation:
Let us evaluate each of the cell types listed regarding their participation in bone formation and remodeling:
- (A) Osteoclasts:
These are large, multinucleated, giant cells derived from the monocyte-macrophage lineage.
They are responsible for bone resorption (dissolving bone matrix and mineral), which is a critical phase of osteogenesis and continuous bone remodeling.
Therefore, (A) is involved.
- (B) Osteoblasts:
These are mononuclear, bone-forming cells derived from osteoprogenitor cells.
They synthesize and secrete the organic components of the bone matrix (osteoid) and facilitate its subsequent mineralization.
Therefore, (B) is involved.
- (C) Osteocytes:
These are mature bone cells trapped within lacunae in the mineralized bone matrix, derived from osteoblasts.
They act as mechanosensors and orchestrate the activity of both osteoblasts and osteoclasts, maintaining bone tissue homeostasis.
Therefore, (C) is involved.
- (D) Fibrocytes:
These are resting, inactive cells of general connective tissue proper (such as in tendons or ligaments) and do not participate directly in the specialized process of osteogenesis.
Therefore, (D) is not involved.
Thus, (A) Osteoclasts, (B) Osteoblasts, and (C) Osteocytes are the cell types that participate in osteogenesis.
Step 3: Final Answer:
The correct option is (B), representing (A), (B) and (C) only.
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