The approach of sequencing the whole set of genome, including all the coding and non-coding sequences in HGP is:
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- Expressed Sequence Tags
- Bioinformatics
- Sequence Annotation
- DNA Polymorphism
The Correct Option is C
Solution and Explanation
The approach of sequencing the whole set of genome, including all the coding and non-coding sequences in the Human Genome Project (HGP) is:
1. Understanding the Concepts:
- Sequence Annotation: This is the process of identifying and marking specific regions in the genome, such as genes, regulatory sequences, and non-coding regions, within the entire genome sequence. The HGP aimed to sequence and annotate the entire human genome, including both coding and non-coding regions.
- Expressed Sequence Tags (ESTs): These are short sequences derived from cDNA, used mainly to identify genes that are actively being expressed. They are not part of the full genome sequencing process.
- Bioinformatics: This field applies computational methods to analyze and interpret biological data, including the analysis of genome sequences, but it is not the sequencing approach itself.
- DNA Polymorphism: Refers to the differences in DNA sequences among individuals within a species, not the complete sequencing and annotation of a genome.
2. Correct Answer:
Sequence Annotation
3. Why This Matters:
Sequence annotation is crucial for understanding the function of the genome. It helps in identifying genes, regulatory elements, and other functional sequences, and it provides a comprehensive map of the human genome, which is the ultimate goal of the Human Genome Project (HGP).
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