Step 1: Understanding the Concept:
Mitosis is the process of nuclear division in eukaryotic cells, which is divided into distinct, sequential stages.
The cell cycle consists of Interphase (G1, S, G2) followed by the M-phase (Mitosis).
Step 2: Detailed Explanation:
The transition from Interphase to Mitosis begins when chromatin starts to condense into highly visible chromosomes.
This initial stage of nuclear division is called Prophase.
During prophase, several key cellular events occur:
Diffuse chromatin fibers condense into distinct chromosomes, each consisting of a pair of sister chromatids.
The nucleolus disappears.
The mitotic spindle begins to form from the centrosomes.
The centrosomes begin migrating to opposite poles of the cell.
Prophase is followed by prometaphase, metaphase, anaphase, and telophase.
Step 3: Final Answer:
The first phase of active mitotic nuclear division is prophase.