Question:

Study the following statements and select the correct option:
Statement (I): Examples of Mendelian disorders are Turner's syndrome and Down's syndrome.
Statement (II): Mendelian disorders are caused due to alteration or mutation in the gene.
Statement (III): Chromosomal disorders are caused due to the absence or excess of one or more chromosomes

Show Hint

Decide which disorders are due to a single gene mutation and which are due to extra or missing chromosomes. Turner and Down syndromes belong to only one of these groups.
Updated On: Nov 12, 2026
  • Statement II is correct and I and III are incorrect
  • Statement I, II and III are correct
  • Statement I is incorrect and II, III are correct
  • Statement I, II and III are incorrect
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The Correct Option is C

Solution and Explanation

Step 1: Understanding the Concept
Mendelian disorders are caused by a mutation in a single gene, for example haemophilia, colour blindness and sickle-cell anaemia.
Chromosomal disorders are due to absence, excess or abnormal arrangement of chromosomes.

Step 2: Statement I
Turner's syndrome (45, XO) and Down's syndrome (trisomy 21) are chromosomal disorders, so statement I is incorrect.

Step 3: Statements II and III
Statement II is correct as Mendelian disorders arise from gene alteration.
Statement III is correct as chromosomal disorders come from missing or extra chromosomes.

Step 4: Conclusion
I is wrong, II and III are right.

Final Answer:
Statement I is incorrect while statements II and III are correct. \[ \boxed{\text{(C) }\text{Statement I is incorrect and II, III are correct}} \]
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