Step 1: Understanding the Concept
Mendelian disorders are caused by a mutation in a single gene, for example haemophilia, colour blindness and sickle-cell anaemia.
Chromosomal disorders are due to absence, excess or abnormal arrangement of chromosomes.
Step 2: Statement I
Turner's syndrome (45, XO) and Down's syndrome (trisomy 21) are chromosomal disorders, so statement I is incorrect.
Step 3: Statements II and III
Statement II is correct as Mendelian disorders arise from gene alteration.
Statement III is correct as chromosomal disorders come from missing or extra chromosomes.
Step 4: Conclusion
I is wrong, II and III are right.
Final Answer:
Statement I is incorrect while statements II and III are correct.
\[ \boxed{\text{(C) }\text{Statement I is incorrect and II, III are correct}} \]