Question:

Statement I: An increase in the concentration of estrogen in circulation causes an increase in the release of gonadotropins.
Statement II: Progesterone decreases the sensitivity of the anterior pituitary to GnRH and decreases LH and FSH concentrations.
In light of the above statements, choose the most appropriate answer from the options given below:

Show Hint

Estrogen: positive feedback on gonadotropins.
Progesterone: negative feedback.
Regulates reproductive cycle.
  • Both Statement I and Statement II are correct
  • Both Statement I and Statement II are incorrect
  • Statement I is correct but Statement II is incorrect
  • Statement I is incorrect but Statement II is correct
Show Solution
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The Correct Option is A

Solution and Explanation

Step 1: Understanding the Concept:
Hormonal regulation involves feedback mechanisms.
Estrogen and progesterone have specific effects.

Step 2: Key Formula or Approach:

No specific formula.
Need to understand hormonal feedback.

Step 3: Detailed Explanation:

Statement I: Estrogen increases gonadotropin release (positive feedback) - correct.
Statement II: Progesterone decreases sensitivity to GnRH and reduces LH/FSH - correct.
Thus, both statements are correct.

Step 4: Final Answer:

Both Statement I and Statement II are correct.
Hence, the correct option is (A).
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