Question

Spindle fibers attach to kinetochores of chromosomes during

• A. Prophase
• B. Metaphase
• C. Anaphase
• D. Telophase

Answer 1

The Correct Option is B

To understand when spindle fibers attach to kinetochores of chromosomes during cell division, we need to consider the stages of mitosis: Prophase, Metaphase, Anaphase, and Telophase.

1. Prophase: Chromosomes condense and become visible. The nuclear envelope begins to break down, and spindle fibers start forming but do not yet attach to kinetochores.
2. Metaphase: This is the key stage where spindle fibers attach to the kinetochores of chromosomes. Chromosomes are aligned at the cell equator, known as the metaphase plate, due to these attachments.
3. Anaphase: Spindle fibers shorten, pulling sister chromatids apart towards opposite poles of the cell.
4. Telophase: Chromosomes reach the poles, the nuclear envelope reforms, and the chromosomes begin to de-condense.

Hence, spindle fibers attach to kinetochores during Metaphase.