Question

Serum bilirubin values have diagnostic importance in jaundice because __________

• A. it is produced by break down of haemoglobin.
• B. it is soluble in water.
• C. fat soluble bilirubin is toxic to brain.
• D. it causes acid reflux.

Hint:

Think about why high bilirubin is dangerous, not just where it comes from.

Answer 1

The Correct Option is C

Step 1: Understanding the Concept
Bilirubin is a yellow pigment formed when the haem of old red blood cells is broken down.

Step 2: Why it matters
Before conjugation in the liver, bilirubin is fat soluble. It can cross the blood-brain barrier and damage brain tissue, especially in newborns.

Step 3: Conclusion
Serum bilirubin tells how severe the jaundice is and whether it is near the toxic level.

Final Answer:
Serum bilirubin is important because fat soluble bilirubin is toxic to the brain. \[ \boxed{\text{(C) }\text{fat soluble bilirubin is toxic to brain.}} \]