Question

Sequence how enzyme converts substrate into products A. Substrate held in the active site by weak interaction B. The active site lower \(E_a\) and speed up the reaction C. Substrate enters into active site, enzyme changes shape D. Substrate are converted to products Choose the correct answer from the options given below:

• A. C$\rightarrow$A$\rightarrow$B$\rightarrow$D
• B. D$\rightarrow$A$\rightarrow$B$\rightarrow$C
• C. B$\rightarrow$C$\rightarrow$D$\rightarrow$A
• D. A$\rightarrow$B$\rightarrow$C$\rightarrow$D

Hint:

Remember enzyme action sequence as: \[ \text{Binding} \rightarrow \text{Catalysis} \rightarrow \text{Product formation} \] Enzymes lower activation energy but do not change equilibrium.

Answer 1

The Correct Option is A

Concept: Enzymes are biological catalysts that accelerate biochemical reactions by lowering activation energy. The catalytic mechanism of enzymes follows a systematic sequence involving:
• Substrate binding
• Formation of enzyme-substrate complex
• Reduction in activation energy
• Product formation This process is highly specific due to the active site of the enzyme.

Step 1: Identify the first event during enzyme action. Initially: \[ \boxed{ \text{Substrate enters the active site} } \] When substrate approaches the enzyme:
• The enzyme slightly changes its shape.
• This is called induced fit mechanism. Thus statement: \[ \boxed{C} \] comes first.

Step 2: Understand substrate binding inside active site. After entering the active site:
• The substrate becomes attached through weak interactions. These weak interactions include:
• Hydrogen bonds
• Ionic interactions
• Van der Waals forces Thus: \[ \boxed{A} \] comes after C.

Step 3: Activation energy is lowered by the enzyme. Once enzyme-substrate complex forms:
• The enzyme stabilizes transition state.
• Activation energy decreases. Hence reaction speed increases. Therefore: \[ \boxed{B} \] comes next.

Step 4: Formation of products occurs finally. After catalytic conversion: \[ \boxed{ \text{Substrate is converted into products} } \] Thus: \[ \boxed{D} \] is the final step.

Step 5: Write the complete sequence. Therefore correct order becomes: \[ \boxed{ C \rightarrow A \rightarrow B \rightarrow D } \] Hence correct answer is: \[ \boxed{(1)} \] Final Conclusion: The enzyme mechanism begins with substrate entry into active site, followed by binding, lowering of activation energy, and finally product formation. \[ \boxed{ C \rightarrow A \rightarrow B \rightarrow D } \]