Question:
Regarding Reye syndrome, the FALSE statement is?
Regarding Reye syndrome, the FALSE statement is?
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Enzymes rise but bilirubin stays normal, so what skin sign is missing?
Updated On: Jun 24, 2026
- Associated with salicylate ingestion
- Hepatomegaly
- Jaundice
- Hypoglycemia
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The Correct Option is C
Solution and Explanation
Step 1: Reye syndrome is an acute, non inflammatory encephalopathy with fatty change in the liver. It damages many organs, especially the brain and liver, and characteristically causes low blood sugar (hypoglycaemia) and a raised ammonia level. So hypoglycaemia (option d) is a true feature.
Step 2: It typically follows a viral illness such as influenza or varicella, classically when salicylates (aspirin) have been given. This confirms that salicylate ingestion (option a) is a true association. The fatty infiltration enlarges the liver, so hepatomegaly (option b) is also true.
Step 3: The liver shows fatty change with minimal inflammation, and liver enzymes rise while bilirubin stays normal. Because bilirubin is not elevated, jaundice is usually absent. Therefore the false statement is jaundice, making option c the answer.
Step 2: It typically follows a viral illness such as influenza or varicella, classically when salicylates (aspirin) have been given. This confirms that salicylate ingestion (option a) is a true association. The fatty infiltration enlarges the liver, so hepatomegaly (option b) is also true.
Step 3: The liver shows fatty change with minimal inflammation, and liver enzymes rise while bilirubin stays normal. Because bilirubin is not elevated, jaundice is usually absent. Therefore the false statement is jaundice, making option c the answer.
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