Concept:
Red Blood Cells (RBCs) carry oxygen in blood using haemoglobin.
Average lifespan of RBCs:
\[
120 \text{ days}
\]
Old and damaged RBCs are mainly destroyed in:
\[
\boxed{\text{Spleen}}
\]
Hence, spleen is often called:
\[
\text{``Graveyard of RBCs''}
\]
Step 1: Understand RBC destruction.
After completing lifespan:
• RBCs become weak
• Spleen filters them
• Macrophages destroy them
Step 2: Understand role of spleen.
Functions of spleen:
• Destruction of old RBCs
• Blood filtration
• Immunity support
Step 3: Analyze options carefully.
Option (A): Kidneys
Involved in urine formation.
Incorrect.
Option (B): Pancreas
Digestive and endocrine gland.
Incorrect.
Option (C): Spleen
Main site of RBC destruction.
Correct.
Option (D): Liver
Liver also helps slightly, but spleen is the primary answer.
Incorrect.
Step 4: Choose the correct answer.
Therefore, RBCs are mainly destroyed in:
\[
\boxed{\text{Spleen}}
\]
Hence,
\[
\boxed{(3)\ \text{Spleen}}
\]