Question:
Radiation sensitivity of the cells to X-rays, in decreasing order is
(A) Skeletal muscle cells
(B) Gut epithelial cells
(C) Lymphoid cells
(D) Germinal cells
Choose the correct answer from the options given below:
Radiation sensitivity of the cells to X-rays, in decreasing order is
(A) Skeletal muscle cells
(B) Gut epithelial cells
(C) Lymphoid cells
(D) Germinal cells
Choose the correct answer from the options given below:
(A) Skeletal muscle cells
(B) Gut epithelial cells
(C) Lymphoid cells
(D) Germinal cells
Choose the correct answer from the options given below:
Show Hint
To remember radiosensitivity hierarchies easily:
- High sensitivity: Lymphocytes, spermatogonia, erythroblasts (germinal cells).
- Intermediate sensitivity: Crypt cells of the gastrointestinal tract, skin basal cells.
- Low sensitivity (Resistant): Muscle cells, nerve cells, osteocytes.
- High sensitivity: Lymphocytes, spermatogonia, erythroblasts (germinal cells).
- Intermediate sensitivity: Crypt cells of the gastrointestinal tract, skin basal cells.
- Low sensitivity (Resistant): Muscle cells, nerve cells, osteocytes.
Updated On: Jul 23, 2026
- (D), (B), (C), (A).
- (C), (B), (D), (A).
- (B), (D), (C), (A).
- (A), (B), (D), (C).
Show Solution
Verified By Collegedunia
The Correct Option is A
Solution and Explanation
Step 1: Understanding the Concept:
The radiosensitivity of cells and tissues to ionizing radiation (such as X-rays) is described by the Law of Bergonié and Tribondeau.
This law states that the radiosensitivity of a cell is directly proportional to its reproductive/mitotic activity and inversely proportional to its degree of differentiation.
Step 2: Detailed Explanation:
Let us analyze the radiosensitivity of the listed cell types from most sensitive to least sensitive (decreasing order):
1. Germinal cells (D):
These are highly undifferentiated stem cells with a very high mitotic rate (such as spermatogonia or erythroblasts).
According to the law of Bergonié and Tribondeau, they are among the most radiosensitive cells in the body.
Therefore, (D) represents the highest sensitivity.
2. Gut epithelial cells (B):
These cells line the crypts of the intestinal mucosa and undergo continuous, rapid division to replace shed epithelial cells.
They are highly sensitive to radiation, but slightly less sensitive than primitive germinal stem cells.
Therefore, (B) represents high to intermediate sensitivity.
3. Lymphoid cells (C):
Although lymphocytes are highly specialized immune cells, they are unique because they are extremely sensitive to radiation-induced apoptosis even when in a non-dividing state.
In general tissue hierarchies, they are highly sensitive, ranking close to germinal cells.
4. Skeletal muscle cells (A):
These are highly differentiated, post-mitotic, non-dividing cells.
Because they lack mitotic activity, they are highly radioresistant, requiring very high doses of radiation to exhibit damage.
Therefore, (A) represents the lowest sensitivity.
Arranging these in decreasing order of radiosensitivity (from most sensitive to least sensitive):
\[ \text{Germinal cells (D)} \rightarrow \text{Gut epithelial cells (B)} \rightarrow \text{Lymphoid cells (C)} \rightarrow \text{Skeletal muscle cells (A)} \]
This corresponds to the sequence (D), (B), (C), (A).
Step 3: Final Answer:
The correct option is (A), representing (D), (B), (C), (A).
The radiosensitivity of cells and tissues to ionizing radiation (such as X-rays) is described by the Law of Bergonié and Tribondeau.
This law states that the radiosensitivity of a cell is directly proportional to its reproductive/mitotic activity and inversely proportional to its degree of differentiation.
Step 2: Detailed Explanation:
Let us analyze the radiosensitivity of the listed cell types from most sensitive to least sensitive (decreasing order):
1. Germinal cells (D):
These are highly undifferentiated stem cells with a very high mitotic rate (such as spermatogonia or erythroblasts).
According to the law of Bergonié and Tribondeau, they are among the most radiosensitive cells in the body.
Therefore, (D) represents the highest sensitivity.
2. Gut epithelial cells (B):
These cells line the crypts of the intestinal mucosa and undergo continuous, rapid division to replace shed epithelial cells.
They are highly sensitive to radiation, but slightly less sensitive than primitive germinal stem cells.
Therefore, (B) represents high to intermediate sensitivity.
3. Lymphoid cells (C):
Although lymphocytes are highly specialized immune cells, they are unique because they are extremely sensitive to radiation-induced apoptosis even when in a non-dividing state.
In general tissue hierarchies, they are highly sensitive, ranking close to germinal cells.
4. Skeletal muscle cells (A):
These are highly differentiated, post-mitotic, non-dividing cells.
Because they lack mitotic activity, they are highly radioresistant, requiring very high doses of radiation to exhibit damage.
Therefore, (A) represents the lowest sensitivity.
Arranging these in decreasing order of radiosensitivity (from most sensitive to least sensitive):
\[ \text{Germinal cells (D)} \rightarrow \text{Gut epithelial cells (B)} \rightarrow \text{Lymphoid cells (C)} \rightarrow \text{Skeletal muscle cells (A)} \]
This corresponds to the sequence (D), (B), (C), (A).
Step 3: Final Answer:
The correct option is (A), representing (D), (B), (C), (A).
Was this answer helpful?
0
0
Top ICAR AIEEA Veterinary Science Questions
- In ox vallate papillae are
- Spiral colon is characteristic of
- Assertion (A) : Stratum lucidum is translucent layer present between stratum spinosum and stratum granulosum
Reasoning (R) : Stratum lucidum is translucent due to presence of eledin protein.
In light of the above statements, choose the correct answer from the options given below. - Statement (I): Keratinocytes contain melanin pigment in the form of melanosomes.
Statement (II): Melanin pigment is produced by keratinocytes with the help of Tyrosinase enzyme.
In light of the above statements, choose the most appropriate answer from the options given below. - Which of the following is true for mast cells?
(A). These cells are common in loose connective tissue.
(B). These cells take metachromatic stain.
(C). These cells are rich in histamine, heparin and proteases.
(D). These cells contain basophilic cytoplasmic granules.
Choose the correct answer from the options given below:
View More Questions
Top ICAR AIEEA Radiology Questions
- For the same amount of absorbed dose in Gray, which of the following will produce maximum ionization and biological hazard?
- Given below are two statements, one is labelled as Assertion (A) and other one labelled as Reason (R).
Assertion (A): Transducer should be placed perfectly parallel to the blood flow to get an insonation angle of 0 to 180 degrees, at the time of Doppler ultrasonography.
Reason (R): At an insonation angle of 0 to 180 degrees, the transducer receives maximum Doppler's shift from the blood flow.
In light of the above statements, choose the most appropriate answer from the options given below. - Given below are two statements, one is labelled as Assertion (A) and other one labelled as Reason (R).
Assertion (A): In ultrasonography, the axial resolution and the maximum available depth of examination is higher for higher frequency transducers.
Reason (R): The high frequency transducers produce shorter pulses with longer pulse interval, and are attenuated early in the tissues due to higher number of interactions.
In light of the above statements, choose the most appropriate answer from the options given below. - Match List-I with List-II
List-I
(A). Hydroquinone
(B). Sodium carbonate
(C). Potassium bromide
(D). Sodium sulfite
List-II
(I). Restrainer
(II). Preservative
(III). Reducing agent
(IV). Accelerator
Choose the correct answer: - Properties of the tungsten that make it a good material for making the anode in an X-ray tube are:
(A). High vapor pressure at high temperature
(B). High atomic number
(C). High melting point
(D). Good thermal conductivity
Choose the correct answer from the options given below:
View More Questions
Top ICAR AIEEA Questions
- Which of the following statements is false?
- Which of the following is an example of an inventory?
- According to Adam Smith, productivity gains could be brought about through .
- The supply curve for an artificially scarce good is .
- Which of the following would not be considered an opportunity cost of paid employment?
View More Questions