Question

Pyruvate is converted to Acetyl CoA by the process of __________

• A. Oxidative Carboxylation
• B. Oxidative decarboxylation
• C. Acetylation and Carboxylation
• D. Reductive decarboxylation

Hint:

Pyruvate loses one carbon as carbon dioxide and is oxidised.

Answer 1

The Correct Option is B

Step 1: Understanding the Concept
Pyruvate enters the mitochondria and is changed to acetyl CoA before the Krebs cycle.

Step 2: Process
Pyruvate loses a carbon as \(\text{CO}_2\) (decarboxylation) and \(\text{NAD}^+\) is reduced to NADH (oxidation).

Step 3: Name
This is oxidative decarboxylation.

Final Answer:
Pyruvate is converted to acetyl CoA by oxidative decarboxylation. \[ \boxed{\text{(B) }\text{Oxidative decarboxylation}} \]