Question:

Processing, packaging the target proteins for export to cell organelles by shuttling is the job of

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Vesicular Transport: Transport Vesicles (COPI, COPII, Clathrin) package and shuttle proteins between ER, Golgi, lysosomes, and the plasma membrane.
  • Plasma membrane
  • Nucleus
  • Endoplasmic reticulum
  • Transport vesicles
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The Correct Option is D

Solution and Explanation


Step 1: Understanding the Concept:

Vesicular trafficking (COPI, COPII, and clathrin-coated vesicles) mediates anterograde and retrograde cargo protein shuttling between endomembrane organelles.

Step 2: Detailed Explanation:

In the eukaryotic secretory and endomembrane trafficking pathway:
- After initial folding in the endoplasmic reticulum and post-translational modification in the Golgi apparatus, target proteins are sorted, concentrated, and packaged into specialized membrane-bound Transport Vesicles (e.g., COPII-coated, COPI-coated, and Clathrin-coated shuttling vesicles).
- These transport vesicles physically bud, travel along microtubule motor tracks (kinesin/dynein), and dock/fuse via v-SNARE/t-SNARE complexes to deliver cargo to lysosomes, secretory granules, and other destination organelles.

Step 3: Final Answer:

Thus, shuttling cargo is the job of Transport vesicles, matching option (D).
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