Question

Nucleotides in RNA are joined by which of the following phosphodiester linkages?

• A. 5$'$–3$'$
• B. 5$'$–2$'$
• C. 3$'$–2$'$
• D. 3$'$–3$'$

Hint:

Remember: both DNA and RNA have 5$'$–3$'$ phosphodiester linkages.

Answer 1

The Correct Option is A

In RNA, each nucleotide is linked to the next through a phosphodiester bond.
This bond forms between the 3$'$–OH of one sugar and the 5$'$–phosphate of the next nucleotide.
Thus, the linkage is called a 5$'$–3$'$ phosphodiester bond.