Question:
Misoprostol, used in the induction of labour, is an analogue of which type of prostaglandin?
Misoprostol, used in the induction of labour, is an analogue of which type of prostaglandin?
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It is the methyl ester analogue, not dinoprostone or carboprost.
Updated On: Jun 23, 2026
- PG E1
- PG E2
- PG I2
- PG F2 alpha
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The Correct Option is A
Solution and Explanation
Step 1: Misoprostol is a synthetic methyl ester analogue of prostaglandin E1 (PGE1).
Step 2: In obstetrics it is used for cervical ripening and, given transvaginally or orally, for induction of labour and medical abortion.
Step 3: Distinguish it from dinoprostone, which is PGE2, and from carboprost, which is the PGF2 alpha (15-methyl) analogue used for atonic postpartum hemorrhage.
Step 4: PGI2 (prostacyclin) is a vasodilator and antiplatelet agent, not a labour-inducing drug. So the answer is PGE1.
Ref: Dutta Obstetrics, 8th ed.
Step 2: In obstetrics it is used for cervical ripening and, given transvaginally or orally, for induction of labour and medical abortion.
Step 3: Distinguish it from dinoprostone, which is PGE2, and from carboprost, which is the PGF2 alpha (15-methyl) analogue used for atonic postpartum hemorrhage.
Step 4: PGI2 (prostacyclin) is a vasodilator and antiplatelet agent, not a labour-inducing drug. So the answer is PGE1.
Ref: Dutta Obstetrics, 8th ed.
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