Question

Match the process in Column I with the action in Column II. {|l|c|l|c|} \multicolumn{2}{|c|}{Column I} & \multicolumn{2}{c|}{Column II}
i. & Tailing & a. & Removal of introns
ii. & Capping & b. & Polyadenylation
iii. & Translation & c. & Addition of mG\textsubscript{ppp} at 5' end of hnRNA
iv. & Splicing & d. & Movement of ribosome on mRNA
Choose the correct match from the options given below.

• A. i - b ii - c iii - a iv - d
• B. i - b ii - a iii - c iv - d
• C. i - b ii - c iii - d iv - a
• D. i - a ii - b iii - c iv - d

Hint:

- Tailing = Poly-A tail - Capping = 5' cap (m\textsubscript{Gppp}) - Splicing = intron removal - Translation = ribosome movement

Answer 1

The Correct Option is C

Concept:
Post-transcriptional modifications and translation:
• Tailing $\rightarrow$ addition of poly-A tail (polyadenylation)
• Capping $\rightarrow$ addition of modified guanine (m\textsubscript{Gppp}) at 5' end
• Translation $\rightarrow$ ribosome moves along mRNA
• Splicing $\rightarrow$ removal of introns

Step 1: Match processes

• i (Tailing) $\rightarrow$ b (Polyadenylation)
• ii (Capping) $\rightarrow$ c (5' cap addition)
• iii (Translation) $\rightarrow$ d (Ribosome movement)
• iv (Splicing) $\rightarrow$ a (Removal of introns)

Step 2: Final mapping
\[ i-b,\quad ii-c,\quad iii-d,\quad iv-a \]