Question

Match List - I with List - II. Match the cell type and their functon : 

Choose the correct answer from the options given below : 
 

• A. A-II, B-IV, C-III, D-I
• B. A-I, B-III, C-IV, D-II
• C. A-III, B-I, C-IV, D-II
• D. A-III, B-IV, C-I, D-II

Hint:

B cells = Bone marrow = humoral immunity = Antibodies. T cells = Thymus = cell-mediated immunity = Cytotoxic killing & Helper Cytokine signalling.

Answer 1

The Correct Option is C

Step 1: Concept:
This question maps major cells of the innate and adaptive immune systems to their primary physiological mechanisms of action.

Step 2: Step-by-step Explanation:

• A. Macrophages: These are large innate immune cells whose primary function is to engulf and digest cellular debris, foreign substances, and microbes. This process is called Phagocytosis. (A $\rightarrow$ III)

• B. B lymphocytes (B cells): These are the center of the humoral adaptive immune system. Upon activation, they differentiate into plasma cells, which produce and secrete antibodies. (B $\rightarrow$ I)

• C. T lymphocytes (T cells): This is a broad category, but specifically points toward Cytotoxic T cells ($CD8^+$), which directly interact with infected host cells (or cancerous cells) and induce apoptosis to destroy the intracellular pathogen factory. (C $\rightarrow$ IV)

• D. Helper T Cells ($CD4^+$): These cells do not kill pathogens directly. Instead, they act as the "generals" of the immune system by secreting stimulatory cytokines that activate B cells, cytotoxic T cells, and macrophages. (D $\rightarrow$ II)
The complete matching sequence is A-III, B-I, C-IV, D-II.

Step 3: Final Answer:
This logical pairing matches option (C).