Question

Match List-I with List-II

Choose the correct answer from the options given below:

• (A) - (II), (B) - (III), (C) - (IV), (D) - (I)
• (A) - (IV), (B) - (III), (C) - (I), (D) - (II)
• (A) - (IV), (B) - (I), (C) - (II), (D) - (III)
• (A) - (III), (B) - (II), (C) - (IV), (D) - (I)

Hint:

To solve this quickly, match Splicing with the removal of introns (B - I), and UniProt as a major Protein Database (D - III), which leaves option (C) as the only possible answer.

Answer 1

The Correct Option is C

Step 1: Understanding the Concept:
Modern molecular biology and bioinformatics rely on specialized experimental methods and curated digital databases to characterize, align, and store sequence and protein data.

Step 2: Detailed Explanation:
Let us match each term from List-I with its corresponding description in List-II:
(A) Orthologues are homologous genes in different species that evolved from a common ancestral gene via speciation (IV).
They typically perform similar biological functions in different organisms.
(B) Splicing is a post-transcriptional modification process in eukaryotes where non-coding introns are removed (I) from the pre-mRNA transcript and the remaining exons are joined together.
(C) Mass spectrometry is an analytical technique used to measure the mass-to-charge ratio of ions, which is widely used in proteomics for protein identification and protein fingerprinting (II).
(D) UniProt (Universal Protein Resource) is a comprehensive, open-access online protein database (III) that provides protein sequence and functional annotation data.
Combining these matches, we get: (A) - (IV), (B) - (I), (C) - (II), (D) - (III).

Step 3: Final Answer:
This sequence corresponds to option (C).