Elimination approach:
Any option that links pollution to genetic material, or eutrophication to cancer, contradicts the standard definitions used in environmental science and can be discarded immediately. Carcinogens are, by definition, agents that promote cancer formation; air/water pollution is the well-known cause of smog formation; eutrophication is specifically driven by excess nutrient (fertiliser) run-off into water bodies; and genes are structurally located within cells. Since only the sequence (A)-(I), (B)-(II), (C)-(III), (D)-(IV) keeps every term matched to its textbook definition, it is the correct mapping.