Question:
Ketone body formation without glycosuria is seen in?
Ketone body formation without glycosuria is seen in?
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Starvation gives ketosis with low-normal glucose and no urine sugar; DM has glycosuria.
Updated On: Jun 24, 2026
- Diabetes mellitus
- Diabetes insipidus
- Starvation
- Obesity
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Verified By Collegedunia
The Correct Option is C
Solution and Explanation
Step 1: Ketone bodies form when fat is heavily mobilised and carbohydrate availability is low. We need a state that produces ketosis but does NOT spill sugar into urine.
Step 2: In diabetes mellitus there is ketosis, but it is accompanied by hyperglycaemia and glycosuria because blood glucose exceeds the renal threshold. So option a has glycosuria and is excluded.
Step 3: In prolonged starvation the body burns fat for energy and forms ketone bodies, yet blood glucose stays low or normal, so there is no glycosuria. This matches the stem.
Step 4: Why the rest are wrong. Diabetes insipidus is a water balance disorder of ADH with no ketosis. Obesity alone does not cause significant ketosis. Confirmatory point: starvation ketosis gives a positive Rothera's (nitroprusside) test for ketones but a negative Benedict's test as there is no urine sugar. Hence the answer is Starvation.
Step 2: In diabetes mellitus there is ketosis, but it is accompanied by hyperglycaemia and glycosuria because blood glucose exceeds the renal threshold. So option a has glycosuria and is excluded.
Step 3: In prolonged starvation the body burns fat for energy and forms ketone bodies, yet blood glucose stays low or normal, so there is no glycosuria. This matches the stem.
Step 4: Why the rest are wrong. Diabetes insipidus is a water balance disorder of ADH with no ketosis. Obesity alone does not cause significant ketosis. Confirmatory point: starvation ketosis gives a positive Rothera's (nitroprusside) test for ketones but a negative Benedict's test as there is no urine sugar. Hence the answer is Starvation.
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