Question

_______ is not a cardio selective drug among the following beta-blockers.

• A. \( \text{Atenolol} \)
• B. \( \text{Betaxolol} \)
• C. \( \text{Esmolol} \)
• D. \( \text{Timolol} \)

Hint:

Remember the mnemonic "BAM-1" for $\beta_1$ selective blockers (Betaxolol, Atenolol, Metoprolol - although metoprolol is not an option here, it's a common example). Esmolol is also $\beta_1$ selective. Non-selective beta-blockers often end in "-olol" but lack the selectivity.

Answer 1

The Correct Option is D

Cardio-selective beta-blockers primarily block $\beta_1$ receptors, which are mainly found in the heart, with less effect on $\beta_2$ receptors located in the lungs and peripheral vasculature. Atenolol, betaxolol, and esmolol are examples of cardio-selective beta-blockers. Timolol, on the other hand, is a non-selective beta-blocker, meaning it blocks both $\beta_1$ and $\beta_2$ receptors.