Question:
Insulin production by recombinant DNA technology is designed by -----------------.
Insulin production by recombinant DNA technology is designed by -----------------.
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Recall who showed insulin could be made in bacteria by recombinant DNA technology in 1978.
Updated On: Nov 12, 2026
- Edward Sharpey Schafer
- Gilbert and Villa-Komaroff
- Itakura et al.
- Stanley Cohen et al
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The Correct Option is B
Solution and Explanation
Step 1: Understanding the Concept
In 1978 Lydia Villa-Komaroff worked with Walter Gilbert on making insulin by recombinant DNA technology.
Step 2: The method
The (pro)insulin gene was joined into a bacterial plasmid next to a bacterial gene and expressed in E. coli.
Step 3: Why the other options fail
Sharpey-Schafer named the hormone insulin. Itakura and co-workers made chemically synthesised genes for the A and B chains. Stanley Cohen with Boyer built the first recombinant plasmid.
Final Answer:
Gilbert and Villa-Komaroff are credited with designing insulin production by rDNA technology. \[ \boxed{\text{(B) }\text{Gilbert and Villa-Komaroff}} \]
In 1978 Lydia Villa-Komaroff worked with Walter Gilbert on making insulin by recombinant DNA technology.
Step 2: The method
The (pro)insulin gene was joined into a bacterial plasmid next to a bacterial gene and expressed in E. coli.
Step 3: Why the other options fail
Sharpey-Schafer named the hormone insulin. Itakura and co-workers made chemically synthesised genes for the A and B chains. Stanley Cohen with Boyer built the first recombinant plasmid.
Final Answer:
Gilbert and Villa-Komaroff are credited with designing insulin production by rDNA technology. \[ \boxed{\text{(B) }\text{Gilbert and Villa-Komaroff}} \]
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