Step 1: Understanding the Concept
Sickle cell anaemia is caused by a single gene change that gives valine instead of glutamic acid at the sixth position of the beta globin chain of haemoglobin.
Step 2: How carriers are detected
In a heterozygous carrier some haemoglobin is abnormal. Under low oxygen the red blood cells take a sickle shape.
Step 3: Choose the cell type
Red blood cells are a part of blood, so the carrier is identified by microscopic examination of blood cells.
Final Answer:
Carriers of sickle cell anaemia are identified by examining blood cells.
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