Question:
In mutation breeding, which of the following does NOT represent chemical mutagens?
In mutation breeding, which of the following does NOT represent chemical mutagens?
Show Hint
Chemical mutagens change the DNA bases, whereas one of the listed substances only doubles the chromosome number.
Updated On: Nov 12, 2026
- Colchicine
- Methyl methane sulphonate
- Sodium azide
- Hydroxylamine
Show Solution
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The Correct Option is A
Solution and Explanation
Step 1: Understanding the Concept
In mutation breeding, chemical mutagens such as alkylating agents, sodium azide and hydroxylamine alter the bases of DNA and so cause gene mutations.
Step 2: Check each option
Methyl methane sulphonate is an alkylating agent, sodium azide and hydroxylamine are well known base-changing mutagens.
Step 3: Colchicine
Colchicine is an alkaloid that blocks spindle formation and doubles the chromosome number to form polyploids. It does not change the gene sequence, so it is not counted as a chemical mutagen here.
Final Answer:
Colchicine is the one that is not a chemical mutagen. \[ \boxed{\text{(A) }\text{Colchicine}} \]
In mutation breeding, chemical mutagens such as alkylating agents, sodium azide and hydroxylamine alter the bases of DNA and so cause gene mutations.
Step 2: Check each option
Methyl methane sulphonate is an alkylating agent, sodium azide and hydroxylamine are well known base-changing mutagens.
Step 3: Colchicine
Colchicine is an alkaloid that blocks spindle formation and doubles the chromosome number to form polyploids. It does not change the gene sequence, so it is not counted as a chemical mutagen here.
Final Answer:
Colchicine is the one that is not a chemical mutagen. \[ \boxed{\text{(A) }\text{Colchicine}} \]
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