Question

In light chain Immunoglobulin, the Carboxy terminus half of Molecule i.e. Constant (C) region consist of two basic amino acid Sequences named as:

• A. Beta ($\beta$) and Gamma ($\gamma$)
• B. Delta ($\delta$) and Theta ($\theta$)
• C. Alpha ($\alpha$) and Beta ($\beta$)
• D. Kappa ($\kappa$) and Lambda ($\lambda$)

Hint:

Light chains? Think "KL" (Kappa and Lambda).

Answer 1

The Correct Option is D

Step 1: Concept
Antibodies (Immunoglobulins) are Y-shaped proteins consisting of two heavy chains and two light chains.

Step 2: Meaning
Light chains are divided into a variable region (antigen binding) and a constant region.

Step 3: Analysis
There are two distinct types of light chains in mammals, based on the sequence of their constant regions: Kappa ($\kappa$) and Lambda ($\lambda$). A single antibody will have either two $\kappa$ chains or two $\lambda$ chains, never one of each.

Step 4: Conclusion
The constant region sequences are named Kappa and Lambda. Final Answer: (D)