Step 1: The given curve is $y^{2} = px^{3} + q$. Differentiate both sides with respect to $x$.\
\[ 2y \frac{dy}{dx} = 3px^{2} \]
\[ \frac{dy}{dx} = \frac{3px^{2{2y} \]\
Step 2: The point of tangency is $(2, 3)$. Substitute $x=2$ and $y=3$ into the derivative to find the slope of the tangent at this point.\
\[ \left(\frac{dy}{dx}\right)_{(2,3)} = \frac{3p(2)^{2{2(3)} = \frac{3p(4)}{6} = \frac{12p}{6} = 2p \]\
Step 3: The equation of the tangent line is given as $y = 4x - 5$. The slope of this line is $4$.\
Step 4: Since $y = 4x - 5$ is tangent to the curve, the slope of the tangent at $(2,3)$ must be equal to the slope of the line.\
\[ 2p = 4 \]
\[ p = 2 \]\
Step 5: The point $(2, 3)$ lies on the curve $y^{2} = px^{3} + q$. Substitute $x=2$, $y=3$, and $p=2$ into the curve's equation.\
\[ (3)^{2} = (2)(2)^{3} + q \]
\[ 9 = 2(8) + q \]
\[ 9 = 16 + q \]
\[ q = 9 - 16 \]
\[ q = -7 \]\
Step 6: Calculate $p-q$.\
\[ p-q = 2 - (-7) \]
\[ p-q = 2 + 7 \]
\[ p-q = 9 \]