Question

Identify the false statement regarding amide from the following.

• A. Amide is obtained on reaction of amines with acetyl chloride.
• B. Amide is more basic than amine
• C. Acylation of amine is a nucleophilic substitution reaction.
• D. The acylation reaction is carried out in presence of base.

Hint:

The nitrogen lone pair in an amide is delocalised onto the carbonyl group, so amides are less basic than amines.

Answer 1

The Correct Option is B

Step 1: Understanding the Concept
Basicity depends on the availability of the lone pair on nitrogen.

Step 2: Check the statements
In amides the lone pair is delocalised into the carbonyl group by resonance, so it is less available.
Hence amides are less basic than amines, and the statement saying more basic is false.
Acylation of amines with acetyl chloride is nucleophilic substitution carried out in the presence of a base such as pyridine.

Step 3: Conclude
The other three statements are true, so the second statement is the false one.

Final Answer:
The false statement is that an amide is more basic than an amine. \[ \boxed{\text{(B) }\text{Amide is more basic than amine}} \]