Question

Hypersecretion of glucocorticoid leads to________

• A. Cushing's disease
• B. Addison's disease
• C. Grave's disease
• D. Bleeders' disease

Hint:

Hormone clue: Cortisol $\uparrow$ $\rightarrow$ Cushing's
Cortisol $\downarrow$ $\rightarrow$ Addison's

Answer 1

The Correct Option is A

Concept: Glucocorticoids (like cortisol) are hormones secreted by the adrenal cortex and play roles in metabolism, stress response, and immune regulation.
• Hypersecretion of glucocorticoids leads to Cushing's syndrome/disease.
• Hyposecretion leads to Addison's disease.

Step 1: Understand hormone imbalance.
Excess cortisol causes metabolic disturbances like fat redistribution, high blood glucose, and muscle wasting.

Step 2: Identify disease.
• Cushing's disease $\rightarrow$ Excess glucocorticoids
• Addison's disease $\rightarrow$ Deficiency
• Grave's disease $\rightarrow$ Hyperthyroidism
• Bleeder's disease $\rightarrow$ Hemophilia

Step 3: Conclusion.
Thus, hypersecretion of glucocorticoids leads to Cushing's disease. Final Answer: Option (A)