Question:

Histamine is responsible for various physiological effects. Which of the following statements are correct?

• [(I)] Histamine is a potent vasodilator.

• [(II)] Histamine lowers blood pressure by constricting blood vessels.

• [(III)] Histamine is responsible for nasal congestion associated with common cold and allergies.

Show Hint

Antihistamines work by blocking the action of histamine and are commonly used to treat allergies, hay fever and cold-related symptoms.
Updated On: Jun 10, 2026
  • I and II only
  • II and III only
  • I and III only
  • I, II and III
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The Correct Option is C

Solution and Explanation

Concept: Histamine is a biologically active amine released from mast cells and basophils during allergic reactions and inflammatory responses. It plays an important role in vasodilation, allergic reactions, gastric secretion and inflammatory processes.

Step 1: Analyse Statement I Histamine causes dilation of blood vessels. Therefore: \[ \boxed{\text{Statement I is correct}} \]

Step 2: Analyse Statement II Histamine does not lower blood pressure by constricting blood vessels. In fact, it causes vasodilation. Therefore: \[ \boxed{\text{Statement II is incorrect}} \]

Step 3: Analyse Statement III Histamine is released during allergic reactions and contributes to:

• Sneezing

• Nasal congestion

• Runny nose

• Inflammation
Hence: \[ \boxed{\text{Statement III is correct}} \]

Final Conclusion Correct statements are: \[ I \text{ and } III \] Hence the correct option is \[ \boxed{\text{(C)}} \]
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