Question:
Given below are two statements:
Statement (I): Myxedema on the forehead and face, resulting in a puffy appearance and thickened skin folds above the eyes is most common in hypothyroidism.
Statement (II): Above-described signs are also important clinical signs in case diabetes mellites.
In light of the above statements, choose the most appropriate answer from the options given below.
Given below are two statements:
Statement (I): Myxedema on the forehead and face, resulting in a puffy appearance and thickened skin folds above the eyes is most common in hypothyroidism.
Statement (II): Above-described signs are also important clinical signs in case diabetes mellites.
In light of the above statements, choose the most appropriate answer from the options given below.
Statement (I): Myxedema on the forehead and face, resulting in a puffy appearance and thickened skin folds above the eyes is most common in hypothyroidism.
Statement (II): Above-described signs are also important clinical signs in case diabetes mellites.
In light of the above statements, choose the most appropriate answer from the options given below.
Show Hint
Classic endocrine clinical presentations:
- Hypothyroidism \(\rightarrow\) Symmetrical alopecia, weight gain without polyphagia, lethargy, seek warmth, and myxedema (tragic face).
- Diabetes Mellitus \(\rightarrow\) 4 Ps: Polyuria, Polydipsia, Polyphagia, and Progressing weight loss.
- Hypothyroidism \(\rightarrow\) Symmetrical alopecia, weight gain without polyphagia, lethargy, seek warmth, and myxedema (tragic face).
- Diabetes Mellitus \(\rightarrow\) 4 Ps: Polyuria, Polydipsia, Polyphagia, and Progressing weight loss.
Updated On: Jul 14, 2026
- Both Statement (I) and Statement (II) are correct.
- Both Statement (I) and Statement (II) are incorrect.
- Statement (I) is correct but Statement (II) is incorrect.
- Statement (I) is incorrect but Statement (II) is correct.
Show Solution
Verified By Collegedunia
The Correct Option is C
Solution and Explanation
Step 1: Understanding the Concept:
Hypothyroidism is a common endocrine disorder in dogs caused by a deficiency of thyroid hormones.
This deficiency causes a decrease in cellular metabolism and an accumulation of glycosaminoglycans in the dermis.
Step 2: Detailed Explanation:
Let us evaluate both statements:
- Statement (I) is correct:
Myxedema is a classic clinical sign of severe canine hypothyroidism.
It is caused by the accumulation of hyaluronic acid and chondroitin sulfate in the dermis, which binds water and causes non-pitting edema.
This is particularly prominent on the face and forehead, creating a puffy appearance, drooping of the eyelids, and thickened skin folds.
This gives the dog a classic "tragic facial expression".
- Statement (II) is incorrect:
These skin changes are not associated with diabetes mellitus.
The classic clinical signs of diabetes mellitus are polyuria, polydipsia, polyphagia, weight loss, and cataracts.
They are caused by insulin deficiency and subsequent hyperglycemia, not dermis glycosaminoglycan accumulation.
Therefore, Statement (I) is correct, but Statement (II) is incorrect, which corresponds to Option (C).
Step 3: Final Answer:
Statement (I) is correct but Statement (II) is incorrect, matching Option (C).
Hypothyroidism is a common endocrine disorder in dogs caused by a deficiency of thyroid hormones.
This deficiency causes a decrease in cellular metabolism and an accumulation of glycosaminoglycans in the dermis.
Step 2: Detailed Explanation:
Let us evaluate both statements:
- Statement (I) is correct:
Myxedema is a classic clinical sign of severe canine hypothyroidism.
It is caused by the accumulation of hyaluronic acid and chondroitin sulfate in the dermis, which binds water and causes non-pitting edema.
This is particularly prominent on the face and forehead, creating a puffy appearance, drooping of the eyelids, and thickened skin folds.
This gives the dog a classic "tragic facial expression".
- Statement (II) is incorrect:
These skin changes are not associated with diabetes mellitus.
The classic clinical signs of diabetes mellitus are polyuria, polydipsia, polyphagia, weight loss, and cataracts.
They are caused by insulin deficiency and subsequent hyperglycemia, not dermis glycosaminoglycan accumulation.
Therefore, Statement (I) is correct, but Statement (II) is incorrect, which corresponds to Option (C).
Step 3: Final Answer:
Statement (I) is correct but Statement (II) is incorrect, matching Option (C).
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