Question

Given below are two statements:
Statement I: In vasospastic angina, the imbalance occurs when the myocardinal oxygen requirement increases, as during exercise, and coronary blood flow does not increase proportionately.
Statement II: In Prinzmetal’s angina, oxygen delivery decreases as a result of reversible coronary vasospasm. 
In light of the above statements, choose the most appropriate answer from the options given below:

• A. Both Statement I and Statement II are correct
• B. Both Statement I and Statement II are incorrect
• C. Statement I is correct and Statement II are incorrect
• D. Statement I is incorrect and Statement II are correct

Answer 1

The Correct Option is C

The question presents two statements related to types of angina and asks us to identify the correct ones based on our understanding of vasospastic angina and Prinzmetal's angina.

1. Evaluate Statement I: "In vasospastic angina, the imbalance occurs when the myocardial oxygen requirement increases, as during exercise, and coronary blood flow does not increase proportionately."
   • Vasospastic angina, also known as variant angina or Prinzmetal's angina, is characterized by temporary and sudden narrowing of the coronary arteries due to vasospasm, not necessarily related to increased oxygen demand during exercise.
   • Therefore, statement I is not accurate regarding vasospastic angina. Vasospastic angina predominantly deals with reversible spasms and not with fixed stenosis that would cause an imbalance due to increased oxygen demand during exercise.
2. Evaluate Statement II: "In Prinzmetal’s angina, oxygen delivery decreases as a result of reversible coronary vasospasm."
   • Prinzmetal’s angina is indeed characterized by reversible coronary vasospasm, leading to a temporary decrease in oxygen delivery. This typically happens at rest and is not related to increased physical activity.
   • Since this statement precisely describes the mechanism of Prinzmetal's angina, it is a correct description.

Based on the evaluation of both statements:

• Statement I is incorrect as it does not accurately describe the condition of vasospastic/Prinzmetal's angina.
• Statement II correctly describes the mechanism of Prinzmetal's angina.

Thus, the correct answer should be: Statement I is incorrect and Statement II are correct.