Question

Given below are two statements:
Statement I: BLAST compares protein as well as nucleotide sequences in order to identify areas of similarity.
Statement II: Genbank is a repository of data on the phenotypic results of gene knockouts in humans.

• A. Both Statement I and Statement II are correct
• B. Both Statement I and Statement II are incorrect
• C. Statement I is correct but Statement II is incorrect
• D. Statement I is incorrect but Statement II is correct

Hint:

BLAST = Sequence comparison. GenBank = DNA sequence database.

Answer 1

The Correct Option is C

Step 1: Concept
Bioinformatics tools and databases serve specific roles in sequence analysis and data storage.

Step 2: Meaning
BLAST is an algorithm for local alignment, while GenBank is a primary sequence database.

Step 3: Analysis
Statement I is correct: BLAST (Basic Local Alignment Search Tool) is designed to find similarities between biological sequences (DNA or Protein). Statement II is incorrect because GenBank is an open-access, annotated collection of all publicly available DNA sequences, not specifically a phenotypic repository for human gene knockouts.

Step 4: Conclusion
Only Statement I accurately describes the tool mentioned. Final Answer: (C)