Question

Given below are two statements
Statement I: According to Koch’s Postulates, inoculation with disease causing microorganism must be able to produce disease symptoms in the susceptible host
Statement II: According to Koch's Postulates, the microorganism must be recoverable from the diseased host
In light of the above statements, choose the correct answer from the options given below:

• A. Both Statement I and Statement II are true
• B. Both Statement I and Statement II are false
• C. Statement I is true but Statement II is false
• D. Statement I is false but Statement II is true

Hint:

Koch's Postulates follow a logical cycle: find the microbe in a diseased host, grow it in pure culture, inoculate a healthy host to cause disease, and re-isolate the same microbe.

Answer 1

The Correct Option is A

Step 1: Understanding the Concept:
Koch's postulates are a set of four criteria established by Robert Koch in 1884 to identify the causal relationship between a specific pathogenic microbe and a disease.

Step 2: Detailed Explanation:
Let us analyze both statements based on the classical four postulates:
1. The microorganism must be found in abundance in all organisms suffering from the disease, but should not be found in healthy organisms.
2. The microorganism must be isolated from a diseased organism and grown in pure culture.
3. Postulate 3: The cultured microorganism should cause disease when introduced (inoculated) into a healthy, susceptible organism.
This corresponds to Statement I: "inoculation with disease causing microorganism must be able to produce disease symptoms in the susceptible host". Thus, Statement I is true.
4. Postulate 4: The microorganism must be re-isolated (recovered) from the inoculated, diseased experimental host and identified as being identical to the original specific pathogen.
This corresponds to Statement II: "the microorganism must be recoverable from the diseased host". Thus, Statement II is true.
Since both statements are true, the correct option is (A).

Step 3: Final Answer:
Hence, both Statement I and Statement II are true.