Question

Given below are two statements, one is labelled as Assertion (A) and other one labelled as Reason (R).
Assertion (A): Lyase removes the group by the formation of double bonds.
Reason (R): Hydrolase transfers the functional group to water.
Choose the correct answer from the options given below:

• A. Both (A) and (R) are true and (R) is the correct explanation of (A).
• B. Both (A) and (R) are true but (R) is NOT the correct explanation of (A).
• C. (A) is true but (R) is false.
• D. (A) is false but (R) is true.

Hint:

Remember the six enzyme classes in order:
1. Oxidoreductases
2. Transferases
3. Hydrolases (uses water to break bonds)
4. Lyases (breaks bonds without water, forming double bonds)
5. Isomerases
6. Ligases

Answer 1

The Correct Option is B

Step 1: Understanding the Concept:
Enzymes are classified into six major functional classes established by the International Union of Biochemistry and Molecular Biology (IUBMB).

Step 2: Detailed Explanation:
- Assertion analysis: Lyases (EC Class 4) catalyze the cleavage of chemical bonds (like \(\text{C}-\text{C}\), \(\text{C}-\text{O}\), \(\text{C}-\text{N}\)) by mechanisms other than hydrolysis or oxidation, often resulting in the formation of a double bond. This statement is true.
- Reason analysis: Hydrolases (EC Class 3) catalyze the hydrolytic cleavage of bonds by transferring a functional group to water molecules. This statement is true.
- Relationship: Both statements are true, but they describe two different classes of enzymes. The mechanism of hydrolases does not explain how lyases function. Therefore, (R) is not the correct explanation of (A).

Step 3: Final Answer:
Both (A) and (R) are true, but (R) is NOT the correct explanation of (A).