Step 1: Understanding genome.
The genome refers to the complete genetic material of an organism, including all its genes.
Step 2: Prokaryotic genetic organization.
Prokaryotes possess a single, circular chromosome without a nuclear membrane.
Step 3: Identifying the correct definition.
The genome of a prokaryote includes all the genes present on its main chromosome.
Step 4: Conclusion.
Therefore, the genome of a prokaryotic cell is the total number of genes present in the chromosome.