Step 1: Use the identity for cotangent.
The cotangent function satisfies the identity:
\[
\cot x = \frac{1}{\tan x}
\]
So the product becomes:
\[
\cot 10^\circ \times \cot 30^\circ \times \cot 45^\circ \times \cot 60^\circ \times \cot 80^\circ = \frac{1}{\tan 10^\circ \times \tan 30^\circ \times \tan 45^\circ \times \tan 60^\circ \times \tan 80^\circ}
\]
Step 2: Use known values of tangent.
We know the following values:
\[
\tan 45^\circ = 1, \quad \tan 30^\circ = \frac{1}{\sqrt{3}}, \quad \tan 60^\circ = \sqrt{3}
\]
Now, use the identity for complementary angles:
\[
\tan(90^\circ - x) = \cot x
\]
Thus, \( \tan 80^\circ = \cot 10^\circ \). Therefore, the product simplifies to:
\[
\frac{1}{\tan 10^\circ \times \tan 30^\circ \times \tan 45^\circ \times \tan 60^\circ \times \tan 80^\circ}
\]
The final result simplifies to:
\[
\boxed{3}
\]