Question

Drugs that show nonlinear pharmacokinetics have which of the following property

• A. A constant ratio of drug metabolites is formed as the administered dose increase.
• B. The elimination half-life increasing as the administered dose increase
• C. The area under the plasma drug concentration versus time curve increasing in direct proportion to an increase in the administered dose.
• D. Both low and high doses follow first order elimination kinetics

Answer 1

The Correct Option is B

The correct option is (B) : The elimination half-life increasing as the administered dose increase