Question

DNAase is used to treat _________

• A. cystic fibrosis
• B. haemophilia
• C. pituitary dwarfism
• D. burns

Hint:

Recombinant DNAase is marketed as Dornase alfa for cystic fibrosis treatment.

Answer 1

The Correct Option is A

Step 1: Understanding DNAase.
DNAase is an enzyme that breaks down extracellular DNA present in thick mucus secretions.

Step 2: Condition in cystic fibrosis.
In cystic fibrosis, thick and sticky mucus accumulates in the lungs due to the presence of DNA from dead cells, making breathing difficult.

Step 3: Therapeutic role.
DNAase reduces mucus viscosity by degrading DNA, thereby improving airflow in the lungs.

Step 4: Conclusion.
Hence, DNAase is used in the treatment of cystic fibrosis.