Question

Degradation of haemoglobin occurs in the ___________.

• A. Liver
• B. Heart
• C. Bone marrow
• D. Kidney

Hint:

Old RBCs are destroyed in the liver and spleen, where haemoglobin is broken down.

Answer 1

The Correct Option is A

Step 1: Understanding haemoglobin breakdown.
Haemoglobin from worn-out red blood cells is broken down into heme and globin components. This process mainly occurs in organs rich in macrophages.
Step 2: Role of the liver.
The liver plays a key role in haemoglobin degradation. Heme is converted into biliverdin and then bilirubin, which is processed and excreted in bile.
Step 3: Analysis of options.
(A) Liver: Correct — primary site of haemoglobin degradation.
(B) Heart: Incorrect — no role in haemoglobin breakdown.
(C) Bone marrow: Incorrect — mainly involved in RBC formation.
(D) Kidney: Incorrect — involved in excretion, not degradation.
Step 4: Conclusion.
Degradation of haemoglobin occurs mainly in the liver.