Question:
Cyproheptadine stimulates appetite by inhibition of which type of receptor:
Cyproheptadine stimulates appetite by inhibition of which type of receptor:
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Serotonin makes you full; Cyproheptadine blocks Serotonin to make you hungry.
Updated On: May 25, 2026
- Dopamine D2 receptor
- 5-HT2 receptor
- Muscarinic M3 receptor
- $\beta$-adrenergic receptor
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The Correct Option is B
Solution and Explanation
Step 1: Concept
Cyproheptadine is a first-generation antihistamine with additional anti-serotonergic properties.
Step 2: Meaning
Appetite regulation in the hypothalamus involves various neurotransmitters, including serotonin (5-HT).
Step 3: Analysis
Serotonin usually acts as an appetite suppressant. By blocking $5-HT_{2}$ receptors, cyproheptadine removes this suppression, leading to increased appetite.
Step 4: Conclusion
The appetite-stimulating effect is primarily due to its $5-HT_{2}$ antagonism. Final Answer: (b)
Cyproheptadine is a first-generation antihistamine with additional anti-serotonergic properties.
Step 2: Meaning
Appetite regulation in the hypothalamus involves various neurotransmitters, including serotonin (5-HT).
Step 3: Analysis
Serotonin usually acts as an appetite suppressant. By blocking $5-HT_{2}$ receptors, cyproheptadine removes this suppression, leading to increased appetite.
Step 4: Conclusion
The appetite-stimulating effect is primarily due to its $5-HT_{2}$ antagonism. Final Answer: (b)
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