Question:
Choose the correct sequence of events involved in the synthesis of a secretory protein:
Choose the correct sequence of events involved in the synthesis of a secretory protein:
Show Hint
SRP is like a âGPSâ that finds the signal and guides the ribosome to the ER âdocking stationâ (Translocon).
Updated On: May 28, 2026
- D, A, E, B and C
- D, B, C, A and E
- D, B, E, C and A
- D, B, E, A and C
Show Solution
Verified By Collegedunia
The Correct Option is B
Solution and Explanation
Step 1: Concept
Secretory proteins are synthesised through a co-translational translocation pathway involving the ER. Step 2--3: Analysis
Synthesis begins on a free ribosome (D). The SRP binds the signal sequence (B). The complex binds to the SRP receptor on the ER membrane (C). The signal peptide binds to the translocon (A). The signal peptide is cleaved as the protein enters the lumen (E).
Step 4: Conclusion
The correct sequence is D $\to$ B $\to$ C $\to$ A $\to$ E.
Final Answer: (B)
Secretory proteins are synthesised through a co-translational translocation pathway involving the ER. Step 2--3: Analysis
Synthesis begins on a free ribosome (D). The SRP binds the signal sequence (B). The complex binds to the SRP receptor on the ER membrane (C). The signal peptide binds to the translocon (A). The signal peptide is cleaved as the protein enters the lumen (E).
Step 4: Conclusion
The correct sequence is D $\to$ B $\to$ C $\to$ A $\to$ E.
Final Answer: (B)
Was this answer helpful?
0
0
Top CUET PG Zoology Questions
- 'Law of natural selection' was given by-
- Which of the following IUCN category is assigned when a species faces an extremely high or very high risk of extinction in the wild in immediate or near future?
- Aristotle's lantern is a masticating apparatus of
- In the lac operon, the lac repressor prevents the transcription initiation by binding to
- Match List I with List II
List I (Genetic Disorders) List II (Genetic Alteration) A Down syndrome I Gain of X-chromosome B Klinefelter's syndrome II Loss of X-chromosome C Turner's syndrome III Trisomy of chromosome 21 D Cri du chat syndrome IV Deletion of small terminal portion of chromosome 5 Choose the correct answer from the options given below:
View More Questions
Top CUET PG Protein Synthesis Questions
- The ribozyme that catalyses peptide bond formation during prokaryotic protein synthesis is :
- Given below are two statements: one is labelled as Assertion A and the other is labelled as Reason R.
Assertion A: Scaffolding proteins are non-histone chromosomal proteins.
Reason R: Scaffolding proteins are abundant in lysine and Arginine.
In the light of the above statements, choose the most appropriate answer from the options given below : - Given below are two statements: one is labelled as Assertion A and the other is labelled as Reason R.
Assertion A: Treatment of immunoglobulin IgG with β-mercaptoethanol gives rise to two heavy chains and two light chains peptides on SDS-PAGE.
Reason R: β-mercaptoethanol breaks peptide bond at the site of disulphide linkage.
In the light of the above statements, choose the most appropriate answer from the options given below: - Proteins can be separated according to size by following techniques except:
A. Isoelectric focusing
B. SDS-PAGE
C. Ion exchange chromatography
D. Molecular exclusion chromatography
Choose the correct answer from the options given below : - Which of the statements regarding the sequence of events from DNA to RNA to protein to enzyme (hexokinase) is correct? A. The linear sequence of deoxyribonucleotides in the DNA encoding hexokinase is transcribed into an RNA molecule with the complementary ribonucleotide sequence.
B. The RNA sequence is translated into the linear protein chain of hexokinase.
C. The linear sequence of deoxyribonucleotides in the DNA encodes for protein hexokinase.
D. The linear protein chain of hexokinase folds into its native three-dimensional shape, aided by molecular chaperones, to catalyze the phosphorylation of glucose using ATP as the phosphoryl group donor.
Top CUET PG Questions
- Given below are two statements:
Statement I: For Plato the meaning of the word 'Justice' is basically a conception in the mind only.
Statement II: For Plato the meaning of the word 'Justice' is fixed, mind-independently
In the light of the above statements, choose the correct answer from the options given below: - What is the electron count of OS6CO182-?
- XeF4 hydrolysis gives A + B, HF, and Oxygen. Find A and B
- What is more basic in pyrol and pyridine?
- Hydrolysis of Al2C3, Be2?
View More Questions